16 April 2020
• Bringing together complementary services and technology to allow faster identification of effective antibodies with a higher chance of success in development
FairJourney Biologics (Porto, Portugal) and Iontas (Cambridge, UK) today announce a partnership to expedite the identification of effective antibodies for a therapeutic to treat COVID-19 patients.
As COVID-19 continues to impact individuals and societies across the globe, this partnership has been formed in the spirit of bringing together the world’s leading scientific expertise, technologies and laboratory facilities for a single common human goal.
The combination of FairJourney’s premier global technical expertise and extensive immune antibody libraries with Iontas’ next generation Mammalian Display technology will also see leading scientists from both companies join forces in the race to identify antibodies to be used in the development of safe and effective treatments.
The collaboration, between parties that would normally be considered competitors, will take advantage of FairJourney’s deep expertise in Phage Display antibody libraries from immune repertoires and Iontas’ premium, next-generation Mammalian Display technology. RNA from recovering patients, provided by Portugal’s Instituto de Medicina Molecular, will be a key source of antibody genes used for the identification of target antibodies.
This combination will enable the newly created partnership to isolate highly specific, neutralizing SARS-CoV-2 antibodies displaying high affinity and preferential biophysical characteristics. The technology package will facilitate the identification of the right antibody without the need for additional optimization, thereby reducing the risk of delays during development and subsequent scale up to manufacturing.
Maria Pajuelo, Chief Scientific Officer of FairJourney, commented: “Given the current pandemic, and our expertise in exploring the 1,400+ immune libraries built at FairJourney, we felt compelled to engage in an antibody-based intervention for COVID-19. In this challenging environment we are proud to come together with John and his team to combine our individual strengths for a common goal.”
John McCafferty, Chief Executive Officer of Iontas commented: “We are delighted to have formed this partnership with FairJourney. Collectively, we felt it important to apply the best platforms in identifying treatments against COVID-19. We believe by using a broad repertoire of antibody libraries and mammalian display, we can find therapeutic candidates that will progress through manufacturing and ultimately into patients in a speedy timeframe.”
T +351 222 437 510
About FairJourney Biologics
FairJourney Biologics is a leading biologics CRO, providing integrated services across antibody discovery, engineering and production to global biopharma. Founded in 2012 and headquartered in Porto, FairJourney has grown to over 90 highly technically skilled employees today. The Company operates a flexible, customer-oriented ‘one-stop shop’ approach to biologics development focused on quality, reliability and partnership. FairJourney has successfully completed more than 460 projects for over 70 customers across big pharma and leading biotech companies to date. The Company’s significant expertise in phage display technology, combined with a diverse approach to generating both immune and naïve antibody libraries have contributed to a market leading 99%+ project success rate. www.fjb.pt
IONTAS is a biotechnology company focused on antibody discovery and cutting-edge technology development. IONTAS offers services for antibody discovery using Phage Display Technology and Mammalian Display. The innovative Mammalian Display platform enables full length antibodies to be expressed in the context of a mammalian cell, thereby allowing selection based on function, stability, expression and developability. www.iontas.co.uk