Our team has published several high impact research papers on many core technology advances in the field.

No Results Found
The page you requested could not be found. Try refining your search, or use the navigation above to locate the post.

Selection of Antibodies Interfering with Cell Surface Receptor Signaling Using Embryonic Stem Cell Differentiation
Publication: Methods Mol. Biol. January 2016. 1341: 111-32 PMID: 26036698. Authors: Melidoni AN, Dyson, MR, McCafferty J
Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2)
Publication: Biochem. J. November 2015, 471 (3): 391-401 PMID: 26303525. Authors: Santamaria S, Yamamoto K, Botkjaer K,, Tape C, Dyson MR, McCafferty J, Murphy G, Nagase H
Identification of optimal protein binders through the use of large genetically encoded display libraries
Publication: Curr . Opin. Chem. Biol.. June 2015. 26: 16-24 PMID: 25626152. Authors: McCafferty J, Schofield D
Temporal- and embryonic lineage-dependent regulation of human vascular SMC development by Notch3
Publication: Stem Cells Dev.. December 2014. PMID: 25539150. Authors: Granata A, Bernard WG, Zhao N, McCafferty J, Lilly B, Sinha S
Targeting the sheddase activity of ADAM17 by an anti-ADAM17 antibody D1(A12) inhibits head and neck squamous cell carcinoma cell proliferation and motility via blockage of bradykinin induced HERs tran
Publication: Int J Biol Sci. Jun. June 2014, 10 (7): 702-14 PMID: 25013379. Authors: Huang Y, Benaich N, Tape C, Kwok HF, Murphy G
Development of a ‘mouse and human cross-reactive’ affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy
Publication: Protein Eng. Des. Sel.. March 2014. 27:179 PMID: 24769623. Authors: Kwok HF, Botkjaer KA, Tape CJ, McCafferty J, Murphy G
Phenotypic directed antibody selection
Publication: Chem. Biol.. February 2014, 21 (2): 170 doi:10.1016/j.chembiol.2014.02.004 PMID: 24560164. Authors: McCafferty J
Expression screening in mammalian suspension cells
Publication: Methods Mol. Biol.. October 2013. 1091:143-9 doi:10.1007/978-1-62703-691-7_9 PMID: 24203329. Authors: Chapple SD, Dyson MR